259 Python Software Engineer Jobs in San Francisco

• P

  Member of Technical Staff (Software Engineer, Training Infrastructure)

  Perplexity · San Francisco

  • Python
  • Rust
  • C++
  • AWS

  $220K – $405K / yr

  Posted today

• P

  Member of Technical Staff (Software Engineer, API Platform)

  Perplexity · San Francisco

  • Python
  • Rust
  • Kubernetes
  • CI/CD

  $220K – $405K / yr

  Posted today

• P

  Member of Technical Staff (Software Engineer, Acceleration)

  Perplexity · San Francisco

  • Python
  • Rust

  $250K – $405K / yr

  Posted today

• C

  Software Engineer, Jade - AI Financial Partner

  Chime · Hybrid · San Francisco, CA, USA

  • Python
  • Ruby
  • Machine Learning
  • LLMs and GenAI

  Posted today

• S

  Firmware Engineer

  Samsara · Remote · Remote - Austin; Remote - Seattle; San Francisco, CA, United States

  • Python
  • Go
  • AWS
  • Linux

  Posted today

• S

  Staff Software Engineer, AI Developer Experience

  SoFi · CA - San Francisco; WA - Seattle

  • Python
  • Java
  • Kotlin
  • Scala

  Posted today

• S

  Principal Software Engineer, Cloud Networking Platform

  SoFi · Hybrid · CA - San Francisco; WA - Seattle; UT - Cottonwood Heights

  • Python
  • AWS
  • Kubernetes

  Posted yesterday

• P

  Principal Software Engineer, ML & Media Infra

  Pinterest · Palo Alto, CA; US; San Francisco, CA, US

  • Python
  • Java
  • C++
  • Machine Learning

  Posted 2 days ago

• D

  Staff Software Engineer, Traffic

  DoorDash · Hybrid · San Francisco, CA; Seattle, WA; New York, NY

  • Python
  • Rust
  • C++
  • AWS

  Posted 2 days ago

• O

  Software Engineer, Traffic Infrastructure

  OpenAI · Onsite · San Francisco

  • Python
  • Go
  • Rust
  • C++

  $266K – $445K / yr

  Posted 2 days ago

• O

  Software Engineer, IP Infrastructure

  OpenAI · Hybrid · San Francisco

  • Python
  • Docker
  • CI/CD

  $266K – $405K / yr

  Posted 2 days ago

• S

  Software Engineer, Fraud System Interventions

  Stripe · South San Francisco, CA

  • Python
  • Java
  • Ruby
  • SQL

  $221K – $286K / yr

  Posted 2 days ago

• M

  Software Engineer, Growth

  Mixpanel · Hybrid · San Francisco, US (Hybrid)

  • TypeScript
  • Python
  • React
  • Django

  Posted 4 days ago

• O

  Staff Software Engineer, AI Platform & Infrastructure

  Okta · San Francisco, California

  • Python
  • SQL
  • React
  • FastAPI

  Posted 7 days ago

• O

  Sr. Software Engineer, AI Platform & Infrastructure

  Okta · San Francisco, California

  • Python
  • SQL
  • React
  • FastAPI

  Posted 7 days ago

• S

  Principal Software Engineer, Data Platform — Data Trust & AI Context

  SoFi · WA - Seattle; UT - Cottonwood Heights; CA - San Francisco

  • Python
  • Java
  • SQL
  • AWS

  Posted 7 days ago

• O

  Software Engineer, Identity Infrastructure

  OpenAI · Hybrid · San Francisco

  • Python
  • Go
  • Rust

  $230K – $325K / yr

  Posted 9 days ago

• M

  Senior Software Engineer, Experimentation

  Mixpanel · Hybrid · San Francisco, US (Hybrid)

  • TypeScript
  • Python
  • React
  • Django

  Posted 9 days ago

• S

  Software Engineer, Context Engine

  Sierra · Onsite · San Francisco, CA

  • TypeScript
  • Python
  • Scala
  • React

  $230K – $390K / yr

  Posted 9 days ago

• S

  Software Engineer, Horizon

  Sierra · Onsite · San Francisco, CA

  • TypeScript
  • Python
  • React
  • LLMs and GenAI

  $230K – $390K / yr

  Posted 9 days ago

• A

  Staff Software Engineer, Finance Engineering

  Anthropic · Hybrid · San Francisco, CA | Seattle, WA

  • Python
  • Java
  • Rust
  • SQL

  Posted 9 days ago

• B

  Senior Software Engineer II, Decisioning Studio Integrations Team

  Braze · Hybrid · San Francisco

  • Python
  • SQL
  • Google Cloud
  • Kubernetes

  Posted 9 days ago

• O

  Software Engineer, CI/CD & ML Infrastructure

  OpenAI · Hybrid · San Francisco

  • Python
  • Rust
  • C++
  • CI/CD

  $318K – $485K / yr

  Posted 12 days ago

• A

  Staff+ Software Engineer, Memory & Search

  Anthropic · Remote · New York City, NY; New York City, NY | Seattle, WA; Remote-Friendly, United States; San Francisco, CA | New York City, NY | Seattle, WA

  • TypeScript
  • Python
  • Machine Learning
  • LLMs and GenAI

  Posted 12 days ago

• F

  Integration Support Engineer

  Flexport · San Francisco, California, United States

  • JavaScript
  • TypeScript
  • Python
  • SQL

  Posted 12 days ago

• P

  Member of Technical Staff (Software Engineer, Enterprise Agent Evals & Efficiency)

  Perplexity · San Francisco

  • Python
  • Rust
  • Machine Learning
  • LLMs and GenAI

  $220K – $405K / yr

  Posted 12 days ago

• P

  Member of Technical Staff (Software Engineer, Enterprise Trust & Governance)

  Perplexity · San Francisco

  • Python
  • Rust
  • AWS
  • Kubernetes

  $220K – $405K / yr

  Posted 14 days ago

• D

  Staff Software Engineer, Product

  Decagon · San Francisco

  • Python
  • LLMs and GenAI

  $200K – $400K / yr

  Posted 14 days ago

• D

  Senior Software Engineer, Product

  Decagon · San Francisco

  • Python
  • LLMs and GenAI

  $200K – $400K / yr

  Posted 14 days ago

• S

  Staff Software Engineer, Platform & Infrastructure

  Sentry · Hybrid · San Francisco, California

  • Python
  • Java
  • AWS
  • Azure

  $240K – $400K / yr

  Posted 15 days ago

Showing the 30 newest of 259. Create a free account to see them all and get matched automatically.

How many Python software engineer roles in San Francisco are open right now?

258 open postings, read straight from company career pages. Closed postings drop off within hours.

What do Python software engineer roles in San Francisco pay?

Across 107 postings that list a yearly USD salary, the midpoint is $310K. The middle half sits between $263K and $339K.

Who is hiring?

Anthropic (44), OpenAI (41), Perplexity (18), DoorDash (17), Discord (10).

How many are remote or senior?

11% are fully remote and 74% are senior, lead or principal level.

Which skills come up most?

Python, AWS, TypeScript, Kubernetes, LLMs and GenAI, Machine Learning.